Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

Rag & Bone Harrow Boot size EU36.5Rag & Bone Newbury Ivory Leather Boots Booties Size 38 8Rag and Bone Boots - Kendall - 40  Continue reading “Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study”

WAKE-UP Time for Thrombolysis in Acute Stroke?

PUMA SCARPA SUEDE PLATFORM gold - 001WHTgold - 6 1 2 (2000211092861)

By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

Ralph by Ralph Lauren Women's Deandra Sandal, Brown, Size 7.5 US 5.5 UKRalph Lauren Collection Karly Sandals Flat Jelly Beach Ocean bluee 9 195 Ralph Lauren Jaqui dark brown leather riding boots UK 4,5

Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

PUMA Select Men's House of Hackney for PUMA Trinomic R698 Evo Sneakers

By Olivier Lucar
October 16, 2018

Ralph Lauren PURPLE LABEL hi heels 9.5 599 ITALY HOTRalph Lauren Women Purple Label Bliara Brown Suede Caged Sandal 4 Sz 41 BRancho Loco Ladies 5.5B Hand Tooled Brown Mules, Leaf DesignRare adidas indoor court vintage 80s made in taiwan uk9.5 koln bern london malmoRare dansko 38 Tie Lace Oxford Striped shoes Punk Goth RavePuma Select Muse Satin Ep Puma Black Puma White , Sneakers Puma select

Puma shoes Ladies Size 41,

By Connor Emdin
September 26, 2018

RARE New Balance 1400 Made In USA Sneakers M1400MG Forest Green Sz 12 MensRARE SUPER LUXURIOUS Ash Italia Suede Fur Boots New and boxedRare Vintage Women's Riding Motorcycle Boots Black Size US.8 UK.6 EU.38-39Rawhide by Abilene Ladies Brown Embroidered Boot 5151 Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

Rebecca Minkoff Bleecker Too Low-Top Fashion SneakersRebecca Minkoff Womens Black White Sandals 5.5 MRebel by Durango Men's Composite Toe WP Western Brown Boots DDB0122Red Valentino tweed flats with black bow size 8 Continue reading “Restrictive versus Liberal Fluid Therapy in Abdominal Surgery”

Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Puma Suede Classic capulet olive - puma white EU 40,5, Männer, green, 365347 14 Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?


By Martina McGrath, MD
July 18, 2018

Red Wing 8146 Men's 8 Roughneck Moc ToeRed Wing Heritage 8001 Work Oxford gold Russet Portage Men's shoes 08001Red Wing Mens Moc Toe Boots 6 8131 gold Russet Portage Leather 10.5 E Wide NEWRedback USACH 6 Outback Crazy Horse Tan Leather Steel Toe Work Safety Boots PUMA TSUGI SHINSEL FRESH LOW RUNNING MEN SHOES GREY GRAPE 364630-01 SIZE 10 NEW


Item specifics

New with box: A brand-new, unused, and unworn item (including handmade items) in the original packaging (such as ... Read moreabout the condition
EU Shoe Size: 46
Main Colour: Black Modified Item: No


Shoe Size: UK 11

Does not apply

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Puma Vikky Platform Women's Sports shoes Pink 36328715

By Connor Emdin
June 27, 2018

Reebok BS5697 Mens Ridgerider 2.0 Trail Runner- Choose SZ color.Reebok - PUMP RUNNING DUAL MU - SCARPA CASUAL - art. M42235-CReebok BD5570 Zprint 3D Sneaker orange blue 180631Reebok Classic BEMO Mid SE Mens Size 10.5 Black Leather Sneakers shoes 4-113688 Puma white Tsugi Shinsei Lace Wns 101

Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

PUMA Women's Basket Platform NS Wn Black, 8 M US

By Martina McGrath, MD
June 5, 2018

Reebok Classic Leather purplec Glow BS7913 purple halfshoesReebok Classics Classic Leather women Trainers White Lifestyle PUMA Women's Boot Quil Wn Platform

PUMA Women's En Pointe Q2 Jacket - Choose SZ color

Reebok CN3808 Classic DAYTONA DMX Casual shoes black grey red sneakers

By Lea Borgi, MD
May 16, 2018

Reebok DV5150 Royal Dashonic SYL Casual shoes white navy red sneakersReebok Ice Cream Trainers Womens Uk3.5, Sneakers Pharrell,Nike, Adidas, PumaReebok Men CN1235 Pump Supreme Running shoes black grey ivory sneakers Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”