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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?


By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

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By Connor Emdin
September 26, 2018

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Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.ASH - TRONCHETTO women ART. TANK IN PELLE black Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Item specifics

New with box: A brand-new, unused, unworn and undamaged item in its original packaging (such as the original box ... Read moreabout the condition
Brand: Arc'teryx
Material: Synthetic US Shoe Size (Women's): US 7
Modified Item: No Style: Hiking, Approach
UK Shoe Size (Women's): UK 5.5 Width: Medium (B, M)
Features: Arch Support Color: Purple
EUR Shoe Size (Women's): EUR 38.5 Product Line: Approach
Sub Style: Apporach, Hiking Model: Acrux SL GTX
UPC: 806955989007

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

Ash 'Tamara' Platine gold Leather Studded Motorcycle Boot Women Size 39 8.5 M

By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

Auth Christian Louboutin Black Leather & Fabric Knee High Boots Size 36AUTH LUXURY PRADA SNEAKERS SHOES 3S5802 blueE SUEDE NEW 37 37,5 UK 4 Asics - GT-1000 7 G-TX - BLACK NEON LIME - 1012A031

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By Lea Borgi, MD
May 16, 2018

Authentic Designer Prada Mens White Leather High Top Trainers Sneakers Uk 11AUTHENTIC LUXURY PRADA SNEAKERS SHOES 3E5838 RED NEW US 6.5 EU 36,5 37AUTHENTIC Nike Air Jordan Why Not Zer0 2 White Total Crimson Tidal bluee Men size Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”